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A cardiac magnetic resonance substudy of the SUMMIT trial showed that tirzepatide treatment led to a placebo-corrected reduction of left ventricular mass by 11 g ([95% CI 419 g]
Mechanical disruption of these vessels releases blood into interstitial space, forming a visible bruise within hours
Keep in mind that Mounjaro (tirzepatide) is in a slightly different class of medication: As a dual GIP/GLP-1 receptor agonist, it is designed to work on both GLP-1 receptors and GIP (glucose-dependent insulinotropic polypeptide) receptors
Injectable use lacks the same regulatory approval but draws on the same safety mechanisms
Limited Long-Term Evidence: There is limited long-term research
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